KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKP2
All Species:
10
Human Site:
S75
Identified Species:
22
UniProt:
Q13309
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13309
NP_005974.2
424
47761
S75
K
R
L
K
S
K
G
S
D
K
D
F
V
I
V
Chimpanzee
Pan troglodytes
XP_001147537
379
42771
A40
L
S
G
M
G
V
S
A
L
E
K
E
E
P
D
Rhesus Macaque
Macaca mulatta
XP_001093834
422
47441
S75
K
R
L
K
S
K
G
S
E
K
D
F
V
I
V
Dog
Lupus familis
XP_546346
749
81658
N400
K
R
L
K
S
K
G
N
D
K
D
F
V
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z3
424
47748
S75
K
R
V
K
G
K
G
S
D
K
D
F
V
I
I
Rat
Rattus norvegicus
Q9QZH7
276
30442
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007983
443
49750
I102
V
K
E
K
E
F
V
I
V
R
R
P
R
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036659
499
55071
L127
Q
I
D
G
T
A
S
L
N
F
Q
P
S
T
S
Honey Bee
Apis mellifera
XP_395497
484
54314
K108
D
N
S
G
Q
C
D
K
I
N
S
F
Q
S
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780472
456
51238
T71
I
K
P
V
I
E
H
T
T
P
S
P
N
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49286
360
39891
G22
F
E
N
M
K
M
E
G
V
L
I
S
E
W
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
91.9
52.3
N.A.
86.3
23.5
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
30
27.8
N.A.
31.3
Protein Similarity:
100
89.3
94.5
54.6
N.A.
92.9
36.7
N.A.
N.A.
74.4
N.A.
N.A.
N.A.
50.9
50.6
N.A.
50
P-Site Identity:
100
0
93.3
93.3
N.A.
80
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
0
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
20
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
10
0
28
0
37
0
0
0
10
% D
% Glu:
0
10
10
0
10
10
10
0
10
10
0
10
19
0
0
% E
% Phe:
10
0
0
0
0
10
0
0
0
10
0
46
0
0
0
% F
% Gly:
0
0
10
19
19
0
37
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
10
0
0
10
10
0
10
0
0
37
10
% I
% Lys:
37
19
0
46
10
37
0
10
0
37
10
0
0
0
10
% K
% Leu:
10
0
28
0
0
0
0
10
10
10
0
0
0
10
10
% L
% Met:
0
0
0
19
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
10
10
10
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
10
0
28
0
10
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
10
0
10
0
10
% Q
% Arg:
0
37
0
0
0
0
0
0
0
10
10
0
10
0
0
% R
% Ser:
0
10
10
0
28
0
19
28
0
0
19
10
10
10
10
% S
% Thr:
0
0
0
0
10
0
0
10
10
0
0
0
0
10
0
% T
% Val:
10
0
10
10
0
10
10
0
19
0
0
0
37
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _